Premium
Fluoxetine is only antidepressant with better results than placebo in young people
Publication year - 2016
Publication title -
the brown university child and adolescent psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7567
pISSN - 1527-8395
DOI - 10.1002/cpu.30139
Subject(s) - fluoxetine , placebo , antidepressant , adverse effect , psychiatry , placebo response , medicine , psychology , major depressive disorder , alternative medicine , serotonin , anxiety , receptor , pathology , cognition
Whether antidepressants work for children and adolescents is controversial; so is the possibility that they may cause or increase suicidality. Researchers compared various medications and placebo, via meta‐analysis. They found that only fluoxetine was more effective at reducing depressive symptoms than placebo, and also that it was better tolerated than the other medications, with fewer discontinuations due to adverse effects.