Premium
Preparation of Oxazole Acetals from N ‐Propargylamides Enabled by Visible‐Light‐Promoted Selenium‐π‐Acid Catalysis
Author(s) -
Wang Xue Yang,
Zhang Qing Bao,
Jin Xiao Ling,
Wu Li Zhu,
Liu Qiang
Publication year - 2021
Publication title -
chemphotochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 18
ISSN - 2367-0932
DOI - 10.1002/cptc.202000239
Subject(s) - oxazole , catalysis , selectfluor , aromatization , chemistry , photochemistry , visible spectrum , selenium , oxygen , combinatorial chemistry , organic chemistry , materials science , optoelectronics
An unprecedented catalytic system consisting of diselenides, Selectfluor and visible light has been developed for the one‐pot synthesis of oxazole acetals from N ‐propargylamides and alcohols. This system shows the processes of cyclization, aromatization and acetalization, resulting in the construction of multiple carbon‐oxygen bonds. These transformations demonstrate the excellent compatibility of visible‐light promotion with organocatalytic oxidative carbon–oxygen bond formations using air as the terminal oxidant.