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Photoredox‐Mediated Synthesis of β‐Hydroxydithioacetals from Terminal Alkynes
Author(s) -
Manzer Manhas Farah,
Kumar Jaswant,
Raheem Shabnam,
Thakur Pankaj,
Rizvi Masood Ahmad,
Shah Bhahwal Ali
Publication year - 2021
Publication title -
chemphotochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 18
ISSN - 2367-0932
DOI - 10.1002/cptc.202000237
Subject(s) - thiophenol , tandem , chemistry , terminal (telecommunication) , oxidative coupling of methane , combinatorial chemistry , oxidative phosphorylation , photochemistry , organic chemistry , catalysis , materials science , computer science , biochemistry , telecommunications , composite material
A single‐step visible light mediated synthesis of β‐hydroxydithioacetals via oxidative coupling of terminal alkynes with thiophenol is reported. Compared to other multistep strategies, this work presents a rare tandem introduction of disulfides and a hydroxy group at the β‐position in one pot. The reaction is enabled by aerial oxidation, features high efficiency and mild conditions, and is extendable to both aliphatic and aromatic alkynes.