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Improved Reactor Productivity for the Safe Photo‐Oxidation of Citronellol Under Visible Light LED Irradiation
Author(s) -
Hamami Zine Eddine,
Vanoye Laurent,
Fongarland Pascal,
de Bellefon Claude,
FavreRéguillon Alain
Publication year - 2019
Publication title -
chemphotochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 18
ISSN - 2367-0932
DOI - 10.1002/cptc.201800201
Subject(s) - citronellol , irradiation , visible spectrum , methylene blue , chemistry , photochemistry , materials science , nuclear chemistry , catalysis , photocatalysis , chromatography , organic chemistry , optoelectronics , geraniol , physics , nuclear physics , essential oil
A simple continuous flow photochemical reactor was optimized for the safe photo‐oxidation of citronellol into precursors of rose oxide, a flagrance of commercial value. The reactor productivity was increased by a factor of 4 compared to the current literature for a conversion above 99 % and in safe conditions (up to 0.72 mM min −1 mL reactor −1 ). The reactor was based on a classical design described by Booker‐Milburn et al., i. e. multiple loops of perfluoroalkoxy (PFA) tubing wrapped tightly around a visible LED lamp under slug flow conditions. The influence of the type of visible white LED light (6500 K vs. 3000 K), of photosensitizers (tetraphenylporphyrin vs. methylene blue), of solvent (CH 2 Cl 2 vs. MeOH), concentration of citronellol (0.1 M vs. 2 M) and of mass efficiency of the reactors (PFA tubing of 0.75 mm to 0.25 mm) was paramount to increase the productivity of the reactor.