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Dimethinium Heteroaromatic Salts as Building Blocks for Dual‐Fluorescence Intracellular Probes
Author(s) -
Bříza Tomáš,
Králová Jarmila,
Rimpelová Silvie,
Havlík Martin,
Kaplánek Robert,
Kejík Zdeněk,
Reddy Bhupendra,
Záruba Kamil,
Ruml Tomáš,
Mikula Ivan,
Martásek Pavel,
Král Vladimír
Publication year - 2017
Publication title -
chemphotochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 18
ISSN - 2367-0932
DOI - 10.1002/cptc.201700061
Subject(s) - fluorescence , intracellular , mitochondrion , alkyl , chemistry , biophysics , dual role , dual (grammatical number) , biochemistry , combinatorial chemistry , biology , organic chemistry , physics , art , literature , quantum mechanics
A series of fluorescent probes based on 2‐β‐anilidovinyl‐ N ‐alkyl‐heteroaromatic salts was prepared. The selective intracellular localization of these probes in mitochondria and lysosomes was demonstrated. Remarkably, some of the probes exhibit unusual dichromic behavior, whereby, in just one step, the salts can be visualized in mitochondria and lysosomes at fluorescence emission wavelengths distinct from each other (dual emitters).