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Antihypertensive effects of Clonidine
Author(s) -
Lilja Mauno,
Jounela Antti J.,
Juustila Heikki,
Marvola Martti
Publication year - 1979
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1979256864
Subject(s) - clonidine , medicine , pharmacology , anesthesia
The antihypertensive effect of clonidine given either two or three times a day with a diuretic was compared in a double‐blind crossover study in 18 hypertensive patients. In II patients given clonidine three times a day there was better control of blood pressure, although the differences in most instances were of the order of only a few millimeters Hg. There were no differences in the frequency or severity of side effects. Clonidine twice daily with a diuretic appears to be adequate for most patients.