Bioavailability of oral dexamethasone | Zendy

Duggan D. E. | Zendy; Yeh K. C. | Zendy; Matalia N. | Zendy; Ditzler C. A. | Zendy; McMahon F. G. | Zendy

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Bioavailability of oral dexamethasone

Author(s) -

Duggan D. E.,

Yeh K. C.,

Matalia N.,

Ditzler C. A.,

McMahon F. G.

Publication year - 1975

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1002/cpt1975182205

Subject(s) - elixir (programming language) , bioavailability , pharmacokinetics , dexamethasone , pharmacology , plasma concentration , medicine , chemistry , chromatography , computer science , programming language

Bioavailabilities of dexamethasone tablets and elixir in man were evaluated by each of 3 model‐independent methods of pharmacokinetic analysis employing plasma and urinary values as determined by radioimmune assay. There were no significant differences among the results determined by the 3 methods nor between the respective availabilities of the !Wo formulations; the latter averaged 82.6 ± 17.7% for the elixir formulation and 78.0 ± 12.1% for tablets.

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