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Iodine absorption in burn patients treated topically with povidone‐iodine
Author(s) -
Lavelle Kevin J.,
Doedens David J.,
Kleit Stuart A.,
Forney Robert B.
Publication year - 1975
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1975173355
Subject(s) - iodine , iodide , medicine , transaminase , metabolic acidosis , silver iodide , acidosis , absorption (acoustics) , anesthesia , physiology , gastroenterology , chemistry , biochemistry , inorganic chemistry , materials science , emulsion , organic chemistry , composite material , enzyme , silver halide
Povidone‐iodine is used as a topical antimicrobial in burn patients. Although absorption of iodine has been thought to be negligible, several patients have recently.been noted with substantial elevations of serum free iodide. Unexplained abnormalities occurred in several of these patients, renal failure, metabolic acidosis, and elevation of serum glutamic oxaloacetic transaminase. It is conceivable that the large iodide loads noted were at least in part responsible for these abnormalities.