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Contact dermatitis
Author(s) -
Epstein William L.
Publication year - 1974
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1974165part2892
Subject(s) - efferent , contact dermatitis , allergic contact dermatitis , lymphatic system , medicine , afferent , immunology , dermatology , immune system , delayed hypersensitivity , pathology , allergy , anatomy
Contact dermatitis is a common skin condition seen by dermatologists. Allergic contact dermatitis (CD) makes up 20% of the group. It is characterized by a delayed onset, perivascular mononuclear cell infiltrate, and passive transfer by lymphoid cells rather than serum, and thus is generally accepted as a variety of delayed hypersensitivity or cellular immune reaction. This brief review will consider allergic contact dermatitis from three aspects: (1) the afferent limb; (2) the central lymphoid compartment; and (3) the efferent limb.
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