Colestipol and clofibrate in hypercholesterolemia | Zendy

Dujovne Carlos A. | Zendy; Hurwitz Aryeh | Zendy; Kauffman Ralph E. | Zendy; Azarnoff Daniel L. | Zendy

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Colestipol and clofibrate in hypercholesterolemia

Author(s) -

Dujovne Carlos A.,

Hurwitz Aryeh,

Kauffman Ralph E.,

Azarnoff Daniel L.

Publication year - 1974

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1002/cpt1974162291

Subject(s) - clofibrate , triglyceride , crossover study , medicine , placebo , endocrinology , niacin , cholesterol , chemistry , alternative medicine , pathology

The effects of colestipol, clofibrate, and placebo were compared in 30 patients with serum cholesterollevels higher than 250 and triglyceride levels under 150 mg per 100 ml in a crossover fashion during a one‐year period. Colestipol reduced mean serum cholesterol concentration 13%. C lofibrate had a similar effect but aLm significantly decreased triglyceride levels. Four patients expressed nonspecific displeasure with colestipol, and 2 abandoned the study for this reason.

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