Premium
Colestipol and clofibrate in hypercholesterolemia
Author(s) -
Dujovne Carlos A.,
Hurwitz Aryeh,
Kauffman Ralph E.,
Azarnoff Daniel L.
Publication year - 1974
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1974162291
Subject(s) - clofibrate , triglyceride , crossover study , medicine , placebo , endocrinology , niacin , cholesterol , chemistry , alternative medicine , pathology
The effects of colestipol, clofibrate, and placebo were compared in 30 patients with serum cholesterollevels higher than 250 and triglyceride levels under 150 mg per 100 ml in a crossover fashion during a one‐year period. Colestipol reduced mean serum cholesterol concentration 13%. C lofibrate had a similar effect but aLm significantly decreased triglyceride levels. Four patients expressed nonspecific displeasure with colestipol, and 2 abandoned the study for this reason.