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A comparison of intermediate‐dose aspirin and placebo in rheumatoid arthritis
Author(s) -
Multz Carler V.,
Bernhard Gerson C.,
Blechman Wilbur C.,
Zane Sheldon,
Restifo Ronald A.,
Varady John C.
Publication year - 1974
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1974153310
Subject(s) - exacerbation , aspirin , placebo , rheumatoid arthritis , medicine , grip strength , arthritis , surgery , pathology , alternative medicine
This double‐blind study evaluates the time required fOT exacerbation to appear on substituting placebo for aspirin (ASA) in 33 patients with classical or definite rheumatoid arthritis. A daily record of symptoms and weekly grip strength and joint counts were evaluated. Three days of placebo exposure were as effective in demonstrating the anticipated exacerbation as langer exposures.