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Plasma renin response to lithium in psychiatric patients
Author(s) -
Shopsin Baron,
Sathananthan Gregory,
Gershon Samuel
Publication year - 1973
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1973144part1561
Subject(s) - plasma renin activity , lithium (medication) , lithium carbonate , renin–angiotensin system , medicine , plasma levels , endocrinology , psychiatry , chemistry , blood pressure , ion , organic chemistry , ionic bonding
Three hospitalized psychiatric patients with different diagnoses were monitored for plasma renin activity before and after subacute treatment with lithium carbonate. Plasma renin activity rose sharply after the first day on lithium and mean plasma renin values were elevated throughout the first week of treatment, returning to baseline levels during the second week. These changes occurred in all three subiects.