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Plasma levels and absorption of methaqualone after oral administration to man
Author(s) -
Morris Robert N.,
Gunderson Gwendolyn A.,
Babcock Steven W.,
Zaroslinski John F.
Publication year - 1972
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1972135part1719
Subject(s) - methaqualone , absorption (acoustics) , oral administration , liter , plasma levels , plasma concentration , medicine , anesthesia , pharmacology , materials science , composite material
Following oral administration of 300 mg. of methaqualone to 7 subiects there was an average peak plasma level of 3.0 p.g per milliliter in 2 hours. Average plasma half‐life was 2.6 hours. Per cent absorption at each time point after administration indicated that 67 per cent absorption occurred in one hour and 99 per cent was absorbed in 2 hours.