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Effects of a single, large, intravenous iniection of dexamethasone
Author(s) -
Czerwinski Anthony W.,
Czerwinski Anthony B.,
Whitsett Thomas L.,
Clark Mervin L.
Publication year - 1972
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1972135part1638
Subject(s) - dexamethasone , itching , medicine , anesthesia , diluent , surgery , chemistry , nuclear chemistry
In a double‐blind study, 60 normal adult volunteers were infused with 2.0 mg. per kilogram of dexamethasone disodium phosphate or an equal amount of the diluent. The men and women receiving dexamethasone complained within 2 minutes of itching, burning, or tingling, all of which were most intense in the anogenital area, and which subsided within minutes. Prolonging the infusion time minimized or prevented this complaint.