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Use of stable isotopes in pharmacology‐clinical pharmacology
Author(s) -
Knapp Daniel R.,
Gaffney Thomas E.
Publication year - 1972
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1972133307
Subject(s) - isotope , pharmacology , stable isotope ratio , radiochemistry , chemistry , medicine , physiology , toxicology , biology , physics , quantum mechanics
The greatest advantages offered by stable isotopes over their radioactive counterparts is the absence of problems associated with radiation. Absence of possible radiation damage to living systems is very important in human studies, especially in the case of children or pregnant women. Absence of radiation hazard also makes the synthesis and handling of stable isotope‐labeled compounds much simpler.