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Closed designs for sequential clinical trials
Author(s) -
Becktel Jack M.
Publication year - 1970
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1970116781
Subject(s) - simplicity , selection (genetic algorithm) , simple (philosophy) , computer science , preference , clinical trial , design of experiments , mathematics , statistics , artificial intelligence , medicine , philosophy , epistemology , pathology
A collection of new closed sequential designs applicable to clinical trials with the paired preference technique is presented. The designs are simple, consisting of two intersecting straight lines. No advantage other than simplicity is claimed over designs such as those of Bross and Armitage when comparable designs are available, but a broader selection of risk and probability levels is prOVided.