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Aspirin absorption
Author(s) -
Nosaquo Norman De
Publication year - 1970
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1970114611
Subject(s) - aspirin , activated charcoal , ingestion , absorption (acoustics) , medicine , wonder , anesthesia , chemistry , psychology , adsorption , social psychology , physics , organic chemistry , acoustics
The article, “Inhibition of aspirin absorption by activated charcoal and apomorphine” which appeared in CLINICAL PHARMACOLOGY AND THERAPEUTICS, September‐October, 1969, raises several interesting questions. First, the study of 12 adults represents a small sample, and no information is provided regarding the relation of meals and time of ingestion of aspirin, etc., or the weight or age of the subjects. As a result, I am curious about the validity of the conclusion that the study showed “. . . conclusively . . . consistent adsorption of aspirin by activated charcoal takes place in the gastrointestinal tract of man.” Second, since the subjects were all adults and most aspirin accidents occur among children, I wonder whether this is a true picture of what happens.