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Penetration of clindamycin into synovial fluid
Author(s) -
Plott Michael A.,
Roth Henry
Publication year - 1970
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1970114577
Subject(s) - clindamycin , synovial fluid , penetration (warfare) , antibiotics , medicine , pathology , microbiology and biotechnology , biology , mathematics , alternative medicine , operations research , osteoarthritis
The new antibiotic, clindamycin, was administered to 15 patients with joint effusions. Synovial fluid samples obtained at various intervals were analyzed for clindamycin. Results indicate good penetration of clindamycin into the synovial space which appears to be independent of local inflammation.