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Effect of tetracycline, polymyxin B, and rifampin on phagocytosis
Author(s) -
Hoeprich Paul D.,
Martin Catherine H.
Publication year - 1970
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt1970113418
Subject(s) - polymyxin b , tetracycline , phagocytosis , polymyxin , antibiotics , microbiology and biotechnology , bacteria , medicine , peripheral blood , immunology , pharmacology , biology , genetics
Tetracycline, polymyxin B, and rifampin (an investigational, semisynthetic antibiotic) did not affect engulfment or intraleukocyte killing of bacteria by leukocytes derived from the peripheral blood of normal volunteers. The augury of unimpaired phagocytic function in the infected human being under treatment with either of these agents has clinical support.