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Sample size in psychiatric drug research
Author(s) -
Rickels Karl,
McLaughlin Blaine E.
Publication year - 1968
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196895631
Subject(s) - sample size determination , statistical analysis , sample (material) , psychology , medicine , psychiatry , data science , medical physics , computer science , statistics , chemistry , mathematics , chromatography
Since the creation of psychopharmacology as a discipline, great strides have been made in the improvement of clinical research. Investigators have become more experienced and sophisticated, designs more appropriate, measurements more sensitive, statistical approaches to data analysis more powerful, and double‐blind and controlled procedures the accepted standard. But there is still room for improvement. Too frequently, for example, well‐designed studies, conducted by expert investigators, are carried out with inadequate samples, making conclusions drawn from the data collected questionable.