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The hypnotic effects of ethchlorvynol and secobarbital in man
Author(s) -
Bellville J. Weldon,
Forrest William H.,
Stevens Jeffrey,
Beer E. George
Publication year - 1968
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196895625
Subject(s) - secobarbital , hypnotic , crossover study , anesthesia , medicine , psychology , placebo , alternative medicine , pathology , pentobarbital
Findings in a controlled double‐blind crossover clinical study in which secobarbital and ethchlorvynol were studied each at two dose levels are reported. The hypnotic relative potency was calculated from the patients' subjective reports of onset, duration, and quality of sleep. It is estimated in this way that 770 mg. of ethchlorvynol is equivalent to 100 mg. of secobarbital.