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Magnesium pemoline: Stimulant effects on performance of fatigued subjects
Author(s) -
Gelfand Sidney,
Clark Lincoln D.,
Herbert Emily W.,
Gelfand Donna M.,
Holmes Elaine D.
Publication year - 1968
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt19689156
Subject(s) - methylphenidate , stimulant , placebo , anesthesia , dextroamphetamine , amphetamine , magnesium , psychology , pharmacology , medicine , chemistry , psychiatry , attention deficit hyperactivity disorder , alternative medicine , organic chemistry , pathology , dopamine
Magnesium pemoline, 100 mg., as compared to placebo, facilitated performance of fatigued subjects required to do repetitious arithmetic problems for 5 hours. It acted like methylphenidate hydrochloride, 20 mg., and d‐amphetamine, 15 mg., by maintaining speed and accuracy near a predrug base line. Smaller doses of magnesium pemoline, 25 and 50 mg., were not significantly different from placebo.