Magnesium pemoline: Stimulant effects on performance of fatigued subjects | Zendy

Gelfand Sidney | Zendy; Clark Lincoln D. | Zendy; Herbert Emily W. | Zendy; Gelfand Donna M. | Zendy; Holmes Elaine D. | Zendy

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Magnesium pemoline: Stimulant effects on performance of fatigued subjects

Author(s) -

Gelfand Sidney,

Clark Lincoln D.,

Herbert Emily W.,

Gelfand Donna M.,

Holmes Elaine D.

Publication year - 1968

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1002/cpt19689156

Subject(s) - methylphenidate , stimulant , placebo , anesthesia , dextroamphetamine , amphetamine , magnesium , psychology , pharmacology , medicine , chemistry , psychiatry , attention deficit hyperactivity disorder , alternative medicine , organic chemistry , pathology , dopamine

Magnesium pemoline, 100 mg., as compared to placebo, facilitated performance of fatigued subjects required to do repetitious arithmetic problems for 5 hours. It acted like methylphenidate hydrochloride, 20 mg., and d‐amphetamine, 15 mg., by maintaining speed and accuracy near a predrug base line. Smaller doses of magnesium pemoline, 25 and 50 mg., were not significantly different from placebo.

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