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Sequential experimentation and multivariate analysis in the evaluation of a treatment for postoperative intestinal symptoms
Author(s) -
Cattaneo Angelo D.,
Lucchelli Paolo E.,
Boelly,
Maccacaro Giulio A.
Publication year - 1966
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196674429
Subject(s) - placebo , multivariate analysis , multivariate statistics , medicine , statistics , mathematics , alternative medicine , pathology
A mixture of iodochlorhydroxyquinoline and phenanthrolinedione was tested for its action on postoperative intestinal symptoms in man. The double‐blind technique was adopted, and a sequential approach was chosen showing that the preparation is significantly more active than the placebo. The results were confirmed by a discriminatory analysis carried out on the data collected.