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Abstracts
Author(s) -
Moser Robert Harlan
Publication year - 1965
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196563393
Subject(s) - medicine , tetracycline , oxytetracycline , pregnancy , gestation , offspring , antibiotics , biology , genetics , microbiology and biotechnology
This is a brief report of eight mothers whose offspring were found to have unilateral or bilateral cataracts of unknown origin. Three women had taken tetracycline or oxytetracycline “during pregnancy or while breast‐feeding.” One had received tetracycline alone at 10 weeks' gestation; another, oxytetracycline alone at 6 weeks; the third, sulfisoxazole at 7 weeks followed by chloramphenicol and tetracycline; the fourth received meclizine, doxylamine, and dicyclomine at 10 weeks, progesterone from the eighth to twentieth week, and tetracycline and oleandomycin for 2 weeks after parturition. (No doses or exact duration were provided.) Of the remaining women, one took no drugs, another promazine alone, the third received acetylaminophenol alone at 10 to 12 weeks, and the fourth took thenalidine tartrate at 12 weeks, phenylbutylamine and acetozolamine at 24 weeks, and sulfamethoxypyridazine at 10 weeks. (Doses and duration not provided.)