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The respiratory and subjective effects of pentazocine
Author(s) -
Bellville J. Weldon,
Green Jean
Publication year - 1965
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196562152
Subject(s) - pentazocine , depressant , morphine , respiratory system , analgesic , anesthesia , pharmacology , medicine
Pentazocine, a new potent analgesic, was studied to determine the respiratory depressant effects. It is a potent respiratory depressant whose dose‐effect curve slope is not significantly different from that of morphine. In respiratory depressant effect it is estimated that 21 mg. of pentazocine is equivalent to 10 mg. of morphine. However, the time‐effect curve for pentazocine appeared to be different from that of morphine for it achieved a higher initial peak effect and showed a more rapid decline.