Premium
Effect of cigarette smoking on blood coagulation
Author(s) -
Ambrus Julian L.,
Mink Irving B.
Publication year - 1964
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196454428
Subject(s) - partial thromboplastin time , coagulation , thromboplastin , prothrombin time , medicine , cigarette smoke , platelet , smoke , whole blood , thrombin time , anesthesia , chemistry , environmental health , organic chemistry
Eighteen medical students who were not smokers were asked to smoke a cigarette, inhaling as much as possible. Blood samples were obtained before and 5 minutes after smoking. A significant increase was observed in platelet adhesiveness. Whole blood coagulation time, recalcified plasma coagulation time, platelet count, partial thromboplastin time, thromboplastin generation time, and tensile strength of the clot showed changes compatible with increased coagulability; however, these were statistically not significant.