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Primaquine and methemoglobin
Author(s) -
Cowan W. K.,
Evans D. A. Price
Publication year - 1964
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196453307
Subject(s) - primaquine , methemoglobin , methemoglobinemia , medicine , polymorphism (computer science) , pharmacology , biology , genetics , hemoglobin , immunology , anesthesia , malaria , genotype , chloroquine , gene
Methemoglobin formation occurring as a toxic manifestation of primaquine was studied in volunteers to determine whether or not it is an example of genetic polymorphism. No evidence of polymorphism was found.