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Abstracts
Author(s) -
Moser Robert Harlan
Publication year - 1964
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196452233
Subject(s) - primaquine , chloroquine , medicine , scalp , penis , trunk , surgery , malaria , pathology , biology , ecology
A 38‐year‐old man stationed in a known endemic malaria area took 500 mg. chloroquine once a week for a period of 6 months; there were no immediate ill effects. Upon leaving this region, he was given primaquine diphosphate (26.3 mg., equivalent to 15 mg. of primaquine base) once daily for 12 days. After this, chloroquine was resumed. One week later, he noted scaly, erythematous lesions developing on his legs, which soon spread to other areas. Six weeks later, new lesions continued to appear (chloroquine was still being taken once each week). Typical psoriatic lesions appeared on the scalp, face, trunk, palms, legs, and penis. Nail pitting and lesions of the elbows, knees, and intergluteal cleft region were not present.