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Part II. Carcinogenesis associated with foods, food additives, food degradation products, and related dietary factors
Author(s) -
Kraybil H. F.
Publication year - 1963
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt19634173
Subject(s) - food science , food additive , consumer safety , nutrient , essential nutrient , food processing , food products , agriculture , pesticide , ingestion , microbiology and biotechnology , toxicology , environmental health , chemistry , medicine , biology , risk analysis (engineering) , agronomy , biochemistry , ecology , organic chemistry
Since the genesis of tumors may be influenced to a lesser or greater degree by the nutrient environment furnished the host, frequent reference is made to the role of nutrition and dietary factors in carcinogenesis. A current and comprehensive review of nutrition and cancer has been presented by Tannenbaum. While the obvious association of cancer and nutrition was recognized earlier, a comprehensive assessment of the role of food and diet in the induction of neoplasms must more accurately be viewed in relation to the ingestion of food additives, food contamif!ants, processing degradation products, and other dietary components.s, Rapid advances in modem food technology have focused attention on dietary components other than essential nutrients such as food additives and processing degradation products. The utilization of agricultural chemicals as soil fumigants, plant growth regulators, and pesticides which may remain on fruits and vegetables if not adequately removed also contributes food contaminants to the diet of man. More recently, the nuclear detonations in weapons‐testing programs as well as the expanded industrial and medical applications of radiOisotopes have introduced radionuclides into the diet as food contaminants. While many of these materials and identified chemical compounds appearing either as additives, contaminants, or degradation products may not be labeled as poisons toxicologically, their latent effect must be assessed in terms of their potential contribution to induction of cancer.