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Part V. An ametric approach to bioassay
Author(s) -
Bross Irwin D. J.
Publication year - 1962
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt196233369
Subject(s) - obstacle , clinical trial , engineering ethics , imperfect , medical research , management science , computer science , medical physics , risk analysis (engineering) , psychology , medicine , political science , engineering , pathology , law , linguistics , philosophy
In the past decade, the controlled clinical trial has tended to become the basic instrument in clinical pharmacology and other areas of medical research. The remarkably rapid and widespread acceptance of this new instrument should not blind us to its limitations. The controlled clinical trial is a somewhat ponderous and rigid instrument, and if it should freeze in its present imperfect form, it could become an obstacle to future research progress. One way to avoid this fate is to continually add new ideas and techniques to the current ones. A relatively new approach‐the ametric approach‐I believe will be increasingly important in future research studies. In order to provide a more concrete and speCific discussion, I am going to consider the application of the ametric approach to a particular experimental situation.