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Process Improvement for Maximized Therapeutic Innovation Outcome
Author(s) -
Waldman Scott A.,
Terzic Andre
Publication year - 2018
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.929
Subject(s) - process (computing) , business process discovery , risk analysis (engineering) , process management , computer science , outcome (game theory) , business , work in process , economics , marketing , microeconomics , business process , operating system , business process modeling
Deconvoluting key biological mechanisms forms the framework for therapeutic discovery. Strategies that enable effective translation of those insights along the development and regulatory path ultimately drive validated clinical application in patients and populations. Accordingly, parity in What vs. How we transform novel mechanistic insights into therapeutic paradigms is essential in achieving success. Aligning molecular discovery with innovations in structures and processes along the discovery–development–regulation–utilization continuum maximizes the return on public and private investments for next‐generation solutions in managing health and disease.