Process Improvement for Maximized Therapeutic Innovation Outcome | Zendy

Waldman Scott A. | Zendy; Terzic Andre | Zendy

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Process Improvement for Maximized Therapeutic Innovation Outcome

Author(s) -

Waldman Scott A.,

Terzic Andre

Publication year - 2018

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1002/cpt.929

Subject(s) - business process discovery , process (computing) , computer science , risk analysis (engineering) , outcome (game theory) , drug discovery , process management , business , bioinformatics , biology , economics , marketing , work in process , microeconomics , business process modeling , business process , operating system

Deconvoluting key biological mechanisms forms the framework for therapeutic discovery. Strategies that enable effective translation of those insights along the development and regulatory path ultimately drive validated clinical application in patients and populations. Accordingly, parity in What vs. How we transform novel mechanistic insights into therapeutic paradigms is essential in achieving success. Aligning molecular discovery with innovations in structures and processes along the discovery–development–regulation–utilization continuum maximizes the return on public and private investments for next‐generation solutions in managing health and disease.

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