Coxibs, Traditional NSAIDs, and Cardiovascular Safety Post‐PRECISION: What We Thought We Knew Then and What We Think We Know Now | Zendy

Patrono C | Zendy; Baigent C | Zendy

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Coxibs, Traditional NSAIDs, and Cardiovascular Safety Post‐PRECISION: What We Thought We Knew Then and What We Think We Know Now

Author(s) -

Patrono C,

Baigent C

Publication year - 2017

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1002/cpt.696

Subject(s) - nonsteroidal , naproxen , celecoxib , ibuprofen , medicine , clinical practice , intensive care medicine , psychology , pharmacology , alternative medicine , family medicine , pathology

The aim of the present review is to analyze how thinking about the cardiovascular safety of nonsteroidal antiinflammatory drugs has evolved during the past two decades, and discuss to what extent the additional information from the Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen study may alter our current mechanistic understanding and/or clinical practice.

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