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Improving the tools of clinical pharmacology: Goals for 2017 and beyond
Author(s) -
Zineh I,
Abernethy D,
Hop CECA,
Bello A,
McClellan MB,
Daniel GW,
Romine MH
Publication year - 2017
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.530
Subject(s) - clinical pharmacology , pharmacology , medicine , intensive care medicine
Current trends in pronounced late‐stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late‐stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.