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Repurposing Drugs for Cognition in Schizophrenia
Author(s) -
Yang YS,
Marder SR,
Green MF
Publication year - 2017
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.529
Subject(s) - schizophrenia (object oriented programming) , repurposing , affect (linguistics) , cognition , psychiatry , medicine , psychology , ecology , communication , biology
Currently approved treatments for schizophrenia only minimally affect the cognitive features of the illness that are the most closely related to disability. Hence, there is now considerable effort to repurpose drugs for schizophrenia, and to seek agents that can improve cognition by targeting receptor systems other than the dopaminergic system. The results of these studies have been mixed thus far; however, this continues to be a high‐priority area of schizophrenia research and an important unmet need.