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Drug Transporters: Advances and Opportunities
Author(s) -
Govindarajan R,
Sparreboom A
Publication year - 2016
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.454
Subject(s) - transporter , drug discovery , drug , drug development , disposition , pharmacology , medicine , biology , bioinformatics , psychology , genetics , gene , social psychology
Drug transporter research conducted over the last several decades has led to a greatly advanced understanding of the mechanisms underlying the principles of drug absorption and disposition. Although many transporters remain poorly characterized, there is ample evidence that the drug transporter field will ultimately provide vital support to routine patient management, and will play a key role in the discovery, development, and evaluation of innovative, cutting‐edge therapies.