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Interventional Pharmacoeconomics: A Novel Mechanism for Unlocking Value
Author(s) -
Serritella Anthony V.,
Strohbehn Garth W.,
Goldstein Daniel A.,
Lichter Allen S.,
Ratain Mark J.
Publication year - 2020
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.1853
Subject(s) - pharmacoeconomics , dosing , medicine , intensive care medicine , drug , pharmacology
Cancer care’s sustainability is challenged by drug expenditures. In the absence of systemic change, innovation is needed to curtail drug costs. Interventional pharmacoeconomics (IVPE) utilizes clinical research to identify safe, efficacious, cost‐conscious dosing regimens to extract maximum value from expensive therapies. Strategies include de‐escalation of dosage, treatment duration and administration frequency, and substitution with therapeutic alternatives. In this review, we discuss how IVPE strategies have been successfully used and could be implemented going forward.