Premium
Selecting the proper pediatric dose: It is more than size that matters
Author(s) -
Kearns GL
Publication year - 2015
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.168
Subject(s) - disposition , health care , intensive care medicine , health professionals , selection (genetic algorithm) , medicine , psychology , computer science , political science , social psychology , artificial intelligence , law
Appropriate pediatric dose selection remains one of the most vexing clinical problems faced by healthcare professionals who are charged to provide medical care to infants and children. While body size does reflect the ontogeny of processes that govern drug disposition, there are extremes of disease that perturb the expected relationships.