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Therapeutic Challenges in Diabetes Prevention: We Have Not Found the “Exercise Pill”
Author(s) -
Srinivasan S,
Florez JC
Publication year - 2015
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.146
Subject(s) - pill , medicine , diabetes mellitus , family medicine , pharmacology , endocrinology
Type 2 diabetes has become an enormous public health burden, making diabetes prevention a pressing issue. While lifestyle modification is the most effective preventive strategy, it is resource‐intensive and not universally sustainable. We review the evidence on pharmacological options for diabetes prevention, in search of a medication that is efficacious, easy to adhere to, well tolerated, and cost‐effective. With the exception of metformin, most other drugs have either limited efficacy or costly side effects.