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Challenges and Opportunities for Improving the Safety Assessment of Botanical Dietary Supplements: A United States Pharmacopeia Perspective
Author(s) -
OketchRabah Hellen A.,
Roe Amy L.,
MuldoonJacobs Kristi,
Giancaspro Gabriel I.
Publication year - 2018
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1002/cpt.1113
Subject(s) - dietary supplement , ingredient , environmental health , quality (philosophy) , perspective (graphical) , public health , medicine , business , food science , computer science , chemistry , nursing , philosophy , pathology , artificial intelligence , epistemology
The United States Pharmacopeia (USP) is an independent, nonprofit, science‐based organization whose mission is to improve global health through public quality standards for dietary supplements, medicines, and food ingredients. 1 Before developing standards for dietary supplement ingredients, the USP performs an “Admission Evaluation” (Figure 1), which includes an assessment to ascertain that an ingredient does not present a serious health risk. 2 This article discusses the challenges encountered during the evaluation of botanicals and proposes possible solutions.

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