Open AccessNatural Products as a Foundation for Drug Discovery
Author(s) -
Beutler John A.
Publication year - 2019
Publication title -
current protocols in pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 26
eISSN - 1934-8290
pISSN - 1934-8282
DOI - 10.1002/cpph.67
Subject(s) - drug discovery , natural product , natural (archaeology) , foundation (evidence) , government (linguistics) , value (mathematics) , drug , business , product (mathematics) , risk analysis (engineering) , biochemical engineering , medicine , pharmacology , engineering , computer science , chemistry , bioinformatics , biology , political science , law , paleontology , linguistics , philosophy , geometry , mathematics , machine learning , stereochemistry
Many natural products have been used as drugs for the treatment of diverse indications. Although most U.S. pharmaceutical companies have reduced or eliminated their in‐house natural‐product research over the years, new approaches for compound screening and chemical synthesis are resurrecting interest in exploring the therapeutic value of natural products. The aim of this commentary is to review emerging strategies and techniques that have made natural products a viable strategic choice for inclusion in drug discovery programs. Published 2019. U.S. Government.