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DNA‐Guided Programmable Protein Assemblies for Biomedical Applications
Author(s) -
Xu Xuemei,
Han Da
Publication year - 2021
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.202100001
Subject(s) - dna , nanotechnology , computational biology , chemistry , combinatorial chemistry , biophysics , materials science , biology , biochemistry
While the protein assemblies have been found widely existing and playing significant roles in biological systems, their imitation and re‐construction is further boosting more applications in biomedical research, such as enzymatic reaction regulation, sensing, and biomedicine. DNA nanotechnology provides a programmable strategy for the fabrication of nanostructures with unprecedented accuracy on the nanoscale. By linking the DNA nanotechnology with proteins of different functions, the precise construction of DNA‐guided protein assemblies can be achieved for various biomedical applications. This minireview summarizes the recent advances in the programmable protein assemblies on DNA nanoplatforms and discusses the outlook of DNA‐guided protein assemblies in the biomedical research.