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Rational Control of Self‐Recognition of Macroionic γ‐Cyclodextrin by Host‐Guest Interaction with Super‐Chaotropic Borate Cluster Ions
Author(s) -
Chen Jiahui,
Luo Jiancheng,
Bekele Selemon,
Tsige Mesfin,
Liu Tianbo
Publication year - 2020
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.202000536
Subject(s) - chaotropic agent , isothermal titration calorimetry , supramolecular chemistry , chemistry , cyclodextrin , boron , cluster (spacecraft) , self assembly , intermolecular force , molecular recognition , crystallography , hydrophobic effect , molecule , organic chemistry , crystal structure , computer science , programming language
We report a feasible method to control self‐recognition during the self‐assembly of a hydrophilic macroion, phosphate‐functionalized γ‐cyclodextrin (γ‐CD‐P), though host‐guest interactions. We confirmed that γ‐CD‐P can form a host‐guest complex with a super‐chaotropic anion, namely the B 12 F 12 2− borate cluster, by using NMR spectroscopy and isothermal titration calorimetry. The loaded γ‐CD‐P, which has a higher charge density, can be distinguished from the uncomplexed γ‐CD‐P, leading to self‐sorting behavior during the self‐assembly process, confirmed by the formation of two types of individual supramolecular structures ( R h of ca. 57 nm and 18 nm, determined by light scattering) instead of hybrid structures in mixed dilute solution. This self‐recognition behavior is accounted for by the difference in intermolecular electrostatic interactions arising from the loading.