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Guanidiniocarbonyl‐Pyrroles (GCP) – 20 Years of the Schmuck Binding Motif
Author(s) -
Giese Michael,
Niemeyer Jochen,
Voskuhl Jens
Publication year - 2020
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.202000142
Subject(s) - motif (music) , computational biology , nanotechnology , chemistry , combinatorial chemistry , biology , materials science , philosophy , aesthetics
In this Minireview, an overview about the past 20 years of the guanidiniocarbonyl‐pyrrole (GCP) binding motif, which was designed, investigated and applied by Prof. Dr. Carsten Schmuck, is presented. Here we highlight the first steps from design and discovery, initial binding studies, applications in material science to advanced biomedical use in protein modulation and delivery of genetic material.