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Front Cover: Base‐Promoted Formation of an Annelated Pyrrolo‐1,4‐oxazine Ensemble from 1 H ‐pyrrol‐2‐ylmethanol and Propargyl Chloride: A Theoretical and Experimental Study (ChemPlusChem 1/2020)
Author(s) -
Vitkovskaya Nadezhda M.,
Bobkov Alexander S.,
Kuznetsova Svetlana V.,
Shcherbakova Victoriya S.,
Ivanov Andrey V.
Publication year - 2020
Publication title -
chempluschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201900613
Subject(s) - chemistry , reagent , front cover , propargyl , extractor , pyrrole , dilution , base (topology) , ammonium chloride , chloride , alkali metal , cover (algebra) , computational chemistry , medicinal chemistry , organic chemistry , thermodynamics , catalysis , process engineering , mechanical engineering , physics , mathematical analysis , mathematics , engineering
The front cover shows that three different pyrrole derivatives can be obtained from the same starting reagents. The reaction is easily controlled by 1) the ratio of the starting reagents, 2) the amount of alkali, and 3) the degree of dilution. This process can be compared with playing the balalaika (a Russian folk instrument), where, by using just three strings, it is possible to produce beautiful melodies from the same notes. The three strings are associated with the three parameters, and the notes are the starting reagents. The sheets with quantum‐chemical calculations symbolize that the experimental work is based on theoretical investigations. More details are given in the Full Paper by N. M. Vitkovskaya and co‐workers on page 88 in Issue 1, 2020 (DOI: 10.1002/cplu.201900407).