Premium
The Effect of the Phospholipid Bilayer Environment on Cholesterol Crystal Polymorphism
Author(s) -
Varsano Neta,
Beghi Fabio,
Dadosh Tali,
Elad Nadav,
Pereiro Eva,
Haran Gilad,
Leiserowitz Leslie,
Addadi Lia
Publication year - 2019
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201900121
Subject(s) - monoclinic crystal system , triclinic crystal system , front cover , chemistry , phospholipid , polymorphism (computer science) , crystallography , cholesterol , bilayer , lipid bilayer , crystal (programming language) , cover (algebra) , crystal structure , membrane , biochemistry , gene , mechanical engineering , programming language , computer science , genotype , engineering
Invited for this month's cover are the group of Prof. Lia Addadi at the Weizmann Institute of Science, Israel and collaborators at the Università Degli Studi di Milano, Italy, and the ALBA Synchrotron Light Source, Spain. The front cover shows how cholesterol crystals form in macrophage cells and in lipid bilayers of different compositions. Cholesterol monohydrate stable triclinic crystals form in vitro as rhomb‐shaped plates, whereas the monoclinic crystals fold into tubular or helical shapes. Read the full text of the article at 10.1002/cplu.201800632.