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Front Cover: The Effect of the Phospholipid Bilayer Environment on Cholesterol Crystal Polymorphism (ChemPlusChem 4/2019)
Author(s) -
Varsano Neta,
Beghi Fabio,
Dadosh Tali,
Elad Nadav,
Pereiro Eva,
Haran Gilad,
Leiserowitz Leslie,
Addadi Lia
Publication year - 2019
Publication title -
chempluschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201900097
Subject(s) - triclinic crystal system , monoclinic crystal system , front cover , chemistry , phospholipid , polymorphism (computer science) , crystallography , cholesterol , lipid bilayer , crystal (programming language) , crystal structure , cover (algebra) , biochemistry , membrane , genotype , gene , mechanical engineering , engineering , programming language , computer science
The front cover shows how cholesterol crystals form in macrophage cells and in lipid bilayers of different compositions. Stable cholesterol monohydrate triclinic crystals form in vitro as rhomb‐shaped plates, whereas the monoclinic crystals fold into tubular or helical shapes. Which lipid environment favors which polymorph? Do the rods and plates found in atherosclerotic plaques analogously reflect the lipid environment in which the crystals formed? Details are given in the Full Paper by L. Addadi and co‐workers on page 338 in Issue 4, 2019 (DOI: 10.1002/cplu.201800632).