Premium
Self‐Assembly of a β‐Peptide Foldamer: The Role of the Surfactant in Three‐Dimensional Shape Selection
Author(s) -
Gong Jintaek,
Eom Taedaehyeong,
Lee Wonchul,
Roy Arup,
Kwon Sunbum,
Kim Hyungjun,
Lee HeeSeung
Publication year - 2019
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201900027
Subject(s) - chemistry , foldamer , pulmonary surfactant , bromide , crystallography , molecule , adsorption , ionic bonding , diffraction , peptide , electron diffraction , scanning electron microscope , chemical physics , inorganic chemistry , ion , organic chemistry , optics , biochemistry , physics
The effect of a small ionic surfactant, cetyltrimethylammonium bromide (CTAB), on the self‐assembly of a β‐peptide has been systematically studied by using scanning electron microscopy, X‐ray diffraction, selected area electron diffraction, and molecular dynamics (MD) simulations. The latter study suggested that the formation of asymmetric microcrystals may be due to the preferential adsorption of CTAB on {011} and (001) crystal faces. This work provides a plausible rationale for the characteristic 3D morphogenesis of foldectures and elucidates the interaction between the surfactant and organic building block molecules.