Premium
Enhancement of the Electrical Properties of DNA Molecular Wires through Incorporation of Perylenediimide DNA Base Surrogates
Author(s) -
Lin KuoYao,
Burke Anthony,
King Nolan B.,
Kahanda Dimithree,
Mazaheripour Amir,
Bartlett Andrew,
Dibble David J.,
McWilliams Marc A.,
Taylor David W.,
Jocson JonahMicah,
MinaryJolandan Majid,
Gorodetsky Alon A.,
Slinker Jason D.
Publication year - 2019
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201800661
Subject(s) - chemistry , dna , diimide , molecular wire , perylene , base pair , nanoscopic scale , context (archaeology) , nanotechnology , macromolecule , dna origami , a dna , base (topology) , biophysics , molecule , materials science , biochemistry , organic chemistry , paleontology , mathematical analysis , mathematics , biology
DNA has long been viewed as a promising material for nanoscale electronics, in part due to its well‐ordered arrangement of stacked, pi‐conjugated base pairs. Within this context, a number of studies have investigated how structural changes, backbone modifications, or artificial base substitutions affect the conductivity of DNA. Herein, we present a comparative study of the electrical properties of both well‐matched and perylene‐3,4,9,10‐tetracarboxylic diimide (PTCDI)‐containing DNA molecular wires that bridge nanoscale gold electrodes. By performing current‐voltage measurements for such devices, we find that the incorporation of PTCDI DNA base surrogates within our macromolecular constructs leads to an approximately 6‐fold enhancement in the observed current levels. Together, these findings suggest that PTCDI DNA base surrogates may enable the preparation of designer DNA‐based nanoscale electronic components.