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Synthesis of Functionalized Ferrocene Derivatives from Donor−Acceptor Cyclopropanes
Author(s) -
GonzálezPelayo Silvia,
López Luis A.
Publication year - 2018
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201800468
Subject(s) - cyclopropane , ferrocene , acceptor , chemistry , aryl , regioselectivity , ring (chemistry) , combinatorial chemistry , organic chemistry , catalysis , electrochemistry , electrode , physics , alkyl , condensed matter physics
Abstract The TfOH‐catalyzed reaction of aryl‐substituted donor–acceptor cyclopropane derivatives with ferrocene provided new functionalized ferrocene derivatives. This process exhibited a reasonable scope with respect to the cyclopropane component affording the corresponding alkylated ferrocene derivatives in useful yields. An alternative approach to these functionalized ferrocene derivatives involving arylation of a ferrocene‐decorated donor–acceptor cyclopropane derivative is also disclosed. Both processes rely on a facile regioselective ring‐opening of the donor−acceptor cyclopropane.