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Front Cover: Amperometric Detection of dsDNA Using an Acridine‐Orange‐Modified Glucose Oxidase (ChemPlusChem 11/2017)
Author(s) -
Jambrec Daliborka,
Lammers Klaus,
Bobrowski Tim,
Pöller Sascha,
Schuhmann Wolfgang,
Ruff Adrian
Publication year - 2017
Publication title -
chempluschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201700374
Subject(s) - acridine orange , glucose oxidase , dna , covalent bond , chemistry , orange (colour) , front cover , combinatorial chemistry , amperometry , biochemistry , biosensor , biophysics , biology , cover (algebra) , organic chemistry , electrochemistry , electrode , apoptosis , mechanical engineering , food science , engineering
The cover picture shows a novel procedure for the preferential post‐hybridization labeling of double‐stranded DNA based on the intercalating compound acridine orange, which was covalently bound to glucose oxidase. Labeling with a highly active biocatalyst allows for a simple and sequence‐independent amplification of the signal proportional to the amount of hybridized DNA that may be coupled with other amplification strategies. Details are given in the Communication by D. Jambrec et al. on page 1311 in Issue 11, 2017 (DOI: 10.1002/cplu.201700279).